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Total synthesis of Dysidiolide:
Reference: Madnuson, S. R.; Sepp-Lorenzino, L.; Rosen, N.; Danishefsky, S. J. J. Am. Chem. Soc. 1998, 120, 1615. DOI
Keywords: O-H → O-SiMe2tBu • Alkyl-OH → Aldehyde • Pd/Sn-Vinyl+Vinyl-X • Stille coupling • Carbocupration Alkyne • Cu-Vinyl+Alkyne • Singlet oxygen+Diene • Furan+Singlet oxygen • Lactone-5 • Ketone enolate+Alkyl-X • Alkyl-X+Enolate • Wolff-Kishner • Aldehyde → CH2 • Li-Aryl+Aldehyde • Aldehyde+Li-Aryl • Ketone → EnolTriflate • Diels-Alder, Enal •
Reagents: LiCuMe2 • HMPA (solvent) • BH(Et)3-Li+ • SiPh2tBu-Cl • Tf2O • Vinyl-Sulfide • Montmorillonite • Hydrazine • RuO4-Pr4N+, NMO • Furyl-Li • O2 (singlet) • Iodoacetate • Imidazole • SiMe3-OTf •

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