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Total synthesis of DOPA, L- (Monsanto):
Reference: Knowles, W. S. Acc. Chem. Res. 1983, 16, 106-112. DOI, Nobel Lecture
Keywords: Arbusov • N-C(O)R → N-H • Oxidative coupling Li-Phosphine • Mg-Aryl+Phosphinate • Phosphinate+Mg-R • Phosphine oxide → Phosphine • Azlactone • Hydrogenation EnoateEster(asym) • EnoateEster Hydrogenation(asym) • Mg-Aryl+Phosphite • Phosphinate •
Reagents: P(OMe)3 • Aryl-MgX • SOCl2 • Aryl-MgX • LiNiPr2 • CuCl2 • NBu3 • Acetic anhydride • Menthol • Pyridine • DIPAMP • MeI •

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