| Reference: | Zeng, X.; Zeng, F.; Negishi, E. Org. Lett. 2004, 6, 3245-3248. DOI |
| Keywords: | Alkyl-OH -> Aldehyde • O-H -> O-SiMe2tBu • Diol-1,2 cleavage • Li/Br -> Li-Vinyl • Li-Vinyl -> Zn-Vinyl • Si-Alkynyl -> H-Alkynyl • O-SiMe2tBu -> O-H • Peterson -> Enal • Peterson -> Enal • Corey-Fuchs • Pd/Zn-Alkynyl+Vinyl-X • Negishi coupling • Pd/Zn-Alkynyl+Vinyl-X • Negishi coupling • B-Allyl-Ipc+Aldehyde • Aldol-B-Ipc • Carboalumination Alkene • Alkyne Hydrozirconation • Pd/Zn-Vinyl+Vinyl-X • Negishi coupling • Li-Alkynyl -> Zn-Alkynyl • Li/H -> Li-Alkynyl • Fritsch-Buttenberg-Wiechell • CarboxAcid -> CarboxAmide • |
| Reagents: | Chiral catalyst • AlMe3 • O2 • DMSO, (COCl)2 • BuLi(sec) • Acetic acid, trifluoro • SiMe2tBu-Cl • AD-Mix • Periodate, sodium • BuLi(sec) • Acetic acid, trifluoro • PPh3=CBr2 • BuLi(n) • ZrCp2ClH • I2 • Alkynyl-ZnX • Ethylene dibromide • Pd(PPh3)4 • Vinyl-ZnX • BuLi(tert) • Carbonate, potassium • PdCl2(PPh3)2 • Fluoride, Bu4N+ • NEtiPr2 • Alkynyl-ZnX • PdCl2(PPh3)2 • LiNiPr2 • Crotyl-B(Ipc)2 • Hydroxide, lithium • |