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Total synthesis of Cubane New:
Reference: Eaton, P. E.; Cole, T. W. J. Am. Chem. Soc. 1964, 86, 3157. DOI
Keywords: Ketone -> Ketal • Ketal -> Ketone • CarboxAcid -> CarboxCl • CarboxCl -> CarboxPerester • Cyclobutane • Allylic oxidation -> Allyl-Br • Alkene -> Dibromide-1,2 • Dehydrohalogenation -> Enone • Diels-Alder, Enone • Cyclopentadienone • Photochemistry 2+2 • Cyclobutane • Favorskii • Decarboxylation • Mechanism •
Reagents: NBS • Bromine • NHEt2 • Glycol • TsOH • HCl, H2O • Hydroxide, potassium • SOCl2 • Hydroperoxide, tbutyl • Cumene • H2SO4 • Hydroxide, potassium • SOCl2 • Hydroperoxide, tbutyl •

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