| Reference: | Martin, S. F.; Barr, K. J. J. Am. Chem. Soc. 1996, 118, 3299. DOI |
| Keywords: | Li/H -> Li-Furyl • N-Boc -> N-H • CarboxEster -> CarboxAcid • Li-Aryl+Alkyl-X • Mannich, vinylogous • Hydrogenation EneLactone • Hydrogenation EneLactone • Amine+Alkyl-X • Amine-7 • Enolsilane+Imonium • Lactone-5 • Imonium+Enolate • Decarbonylation • Mannich, vinylogous • Enolsilane+Imonium • Imonium+Enolate • Amine-5 • Lactone-5 • |
| Reagents: | SiiPr3-OTf • Furyl-Li • BuLi(sec), TMEDA • Acetic acid, trifluoro • H2, Rh • DMF (solvent) • HBr • POCl3 • H2, Pd • HCl, EtOH • SiiPr3-OTf • |