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Total synthesis of Cantharidin:
Reference: Stork, G.; van Tamelen, E. E.; Friedman, L. J.; Burgstahler, A. W. J. Am. Chem. Soc. 1951, 73, 4501. DOI Stork, G.; van Tamelen, E. E.; Friedman, L. J.; Burgstahler, A. W. J. Am. Chem. Soc. 1953, 75, 384–392. DOI
Keywords: CarboxEster → Alkyl-OH • O-H → O-SO2R • Alkyl-OH → Alkyl-SR • Diels-Alder, Yne • Furan-cycloaddition • Diels-Alder, EnoateEster • Alkene → Diol-1,2 • Alkyl-SR → Alkyl-H • Diol-1,2 cleavage • Li-Aryl+Aldehyde • Dehydration → Ene • Ester Pyrolysis • Ozonolysis • Aldol-enamine → Enal •
Reagents: AlH4-Li+ • Sulfonyl chloride, methane • Thiolate, ethyl • OsO4 • RaNi • Periodic acid • PhLi • O3 • H2O2 • Butadiene • H2, Pd •

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