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Total synthesis of Bigelovin:
Reference: Grieco, P. A.; Ohfune, Y.; Majetich, G. J. Org. Chem. 1979, 44, 3092
Keywords: Enone -> Allyl-OH --- O-Bn -> O-H --- O-H -> O-THP --- Lactone-5 --- O-THP -> O-H --- Allyl-OH -> Enone --- CarboxAcid enolate+Epoxide --- Aldol-Li -> Methylene lactone --- Lactone enolate+Formaldehyde --- O-H -> O-C(O)R --- Epoxidation, peracid --- RC-Alkene/Alkene+Peracid
Reagents: AlH4-Li+ --- Perbenzoic acid, 3-chloro --- LiNiPr2 --- Li°/NH3 --- HCl --- DHP --- Formaldehyde --- MeSO2Cl --- AcOH --- MnO2 --- Ac2O --- CH2=C(OLi)2 --- DMAP

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