image

Total synthesis of Basiliskamide A:
Reference: Lipomi, D. J.; Langille, N. F.; Panek, J. S. Org. Lett. 2004, 6, 3533. DOI
Keywords: O-H → O-SiiPr3 • O-H → O-MOM • O-Bn → O-H • Alkyl-OH → Aldehyde • Takai-Utimoto → Vinyl-I • O-MOM → O-H • O-SiiPr3 → O-H • Pd/Sn-Vinyl+Vinyl-X • Stille coupling • B-Allyl-Tartrate+Aldehyde • Aldol-B-Tartrate • Si-Allyl+Aldehyde • Aldehyde+Si-R • Hydrogenation alkene • Ozonolysis •
Reagents: TiCl4 • SiiPr3-OTf • O3 • Crotyl-B(tartrate) • Chloromethyl ether • NEtiPr2 • H2, Pd • DMSO, (COCl)2 (Swern) • CHI3 • B(Cl)3 • PdCl2(MeCN)2 • Vinyl-SnR3 • HF·Py •

Syntheses Home