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Total synthesis of Bakkenolide:
Reference: Evans, D. A.; Sims, C. L.; Andrews, G. C. J. Am. Chem. Soc. 1977, 99, 5453. DOI
Keywords: Alkene cleavage • Lemieux-Johnson oxidation • CarboxEster(thio) → CarboxEster(thio) • Enone enolate+Alkyl-X • Alkyl-X+Enolate • Aldol-K → Enone • Hydrogenation Enone • Li-Vinyl+Ketone • Enone+Li-R • Allyl-OH → Allyl-Br • Allylic oxidation → Allyl-OH • Lactone-5 • Allyl-X → Allyl-SR • 2,3-Sigmatropic Anionic • Retro-Claisen •
Reagents: KOtBu • Allyl-Cl • Hydroxide, potassium • OsO4, NaIO4 • KOtBu • H2, Pd • Vinyl-Li • PBr3 • Allyl-Br • NaH • HgCl2 • SeO2 • NaH •

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