| Reference: | Carretero, J. J.; Ghosez, L Tetrahedron Lett. 1988, 29, 2059. DOI |
| Keywords: | Ketal -> Diol Orthoester -> CarboxEster Lactone-6 Wittig-alkyl -> Ene-cis Li-Sulfone+Epoxide O-H -> O-SO2R Dehydrosulfonylation -> EneLactone Diol -> Epoxide |
| Reagents: | Ph3P=CH-Alkyl HCl, MeOH NaOMe Epoxide LiCHR-Sulfonyl TsOH NEt3 TsCl, Py |