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Total synthesis of (-)-Argentilactone:
Reference: Carretero, J. J.; Ghosez, L Tetrahedron Lett. 1988, 29, 2059. DOI
Keywords: Ketal → Diol-1,2 • Orthoester → CarboxEster • Lactone-6 • Wittig-alkyl → Ene-cis • Li-Sulfone+Epoxide • O-H → O-SO2R • Dehydrosulfonylation → EneLactone • Diol-1,2 → Epoxide •
Reagents: PPh3=CH-Alkyl • HCl, MeOH • NaOMe • Epoxide • LiCHR-Sulfonyl • TsOH • NEt3 • TsCl, Py •

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