Reference: | Bonjoch, J.; Sole, D.; Garcia-Rubio, S.; Bosch, J. J. Am. Chem. Soc. 1997, 119, 7230. DOI |
Keywords: | Si-Propargyl+Enone Enone+Si-R Amine-6 N-Me → N-C(O)OR Ketone → EnolSilane Ketone → Ketone-α-SeR EnolSilane → Ketone-α-SeR Reductive amination, B-H Amine-5 N-H → N-Alkyl Selenoxide-Ei → Enone Ketone → Enone Claisen acylation, Mander Ketone enolate+Mander N-H → N-Propargyl Nitro → Amine Indole synthesis Hydrogenation Allene Ozonolysis |
Reagents: | Propargyl-Si BF3·OEt2 LiNiPr2 H2, Pd O3 NH2Me O=C(OR)Cl NH(SiMe3)2 (HMDS) SiMe3-I O3 Propargyl-I Carbonate, potassium HCl H2, Pd O=C(OR)CN NHiPr2 BH3CN-Na+ |