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Total synthesis of Actinidiolide:
Reference: Rubottom, G. M.; Juve, H. D. Jr. J. Org. Chem. 1983, 48, 422. DOI
Keywords: EnolSilane → Ketone enolate • Enone → EnolSilane • Dehydrohalogenation → Enone • CarboxEster enolate+Ketone • Aldol-Li → Aldol • Ketone → Ketone-α-Halo • Dehydration → EneLactone • Ketone → EnolSilane • Enone → EnolSilane • Ketone → Ketone-α-OR • EnolSilane+MCPBA • Rubottom oxidation • O-H → O-C(O)R •
Reagents: LiNiPr2 • SiMe3-Cl • MeLi • Bromine • LiNiPr2 • SiMe3-Cl • LiNiPr2 • SOCl2 • Bromide, lithium • Carbonate, lithium • DMF (solvent) • Perbenzoic acid, 3-chloro • HF·NEt3 • Acetic anhydride • DMAP •

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