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Total synthesis of Abscisic Acid:
Reference: Constantino, M. G.; Losco, P.; Castellano, E. E. J. Org. Chem. 1989, 54, 681. DOI
Keywords: Robinson annulation, ketoester • Ketoester enolate+Enone • Ketone → Ketal • EnoateEster → Allyl-OH • Allyl-OH → Enal • Ketal → Ketone • Epoxide → Allyl-OH • Ketone → EnolEther • Epoxidation, peracid • Reformatsky • Enal+Enolate • CarboxEster enolate+Enal • Lactone-6 •
Reagents: Acetoacetate • Orthoformate • ZnCl2 • Glycol • H2SO4 • H2SO4 • AlH4-Li+ • MnO2 • Perbenzoic acid, 3-chloro • Oxalic acid • Hydroxide, sodium • Allyl-Br • Zn° •

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