image

Total synthesis of Codling Moth Compound:
Reference: Marfat, A.; McGuirk, P. R.; Helquist, P. J. Org. Chem., 1979, 44, 1345, 3888
Keywords: O-H -> O-SO2R --- CarboxAcid -> Alkyl-OH --- Cu-Vinyl+Epoxide --- Cu-Vinyl+CO2 --- Carbocupration Alkyne --- Cu-Alkyl+Alkyne --- Carbocupration Alkyne --- Cu-Alkyl+Alkyne --- Alkyl-OH -> Alkyl-I --- Finkelstein reaction
Reagents: Alkyl-MgX --- CuBr·SMe2 --- Propyne --- Alkynyl-Li --- Vinyl-Cu --- Epoxide --- NH4Cl --- TsCl, Py --- Iodide, sodium --- Alkyl-MgX --- Alkyl-MgX --- CuBr·SMe2 --- Vinyl-Cu --- CO2 --- AlH4-Li+

Syntheses Home