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Total synthesis of Coccinelline:
Reference: Stevens, R. V.; Lee, A. W. N. J. Am. Chem. Soc. 1979, 101, 7032
Keywords: Ketone -> Ketal(Me) --- Robinson-Schoepf --- Amine-6 --- Reductive amination, B-H --- Michael Acrolein --- Claisen acylation, ester --- CarboxEster enolate+CarboxEster --- Wittig-methyl --- Amine oxide --- Hydrogenation-Ene(asym) --- Decarboxylation Krapcho --- Decarboxylation Krapcho --- Decarboxylation Krapcho
Reagents: NaOMe --- Chloride, sodium --- NaH --- Chloride, sodium --- NH4OAc --- BH3CN-Na+ --- Acetone dicarboxylate --- Chloride, sodium --- Ph3P=CH2 --- H2, Pd --- Perbenzoic acid, 3-chloro --- Acrolein --- Malonate --- DMF (solvent) --- DMF (solvent) --- DMF (solvent)

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