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Total synthesis of 5-Desoxy-Leucotriene D:
Reference: Corey, E. J.; Hoover, D. J. Tetrahedron Lett., 1982, 23, 3463. DOI
Keywords: O-H → O-C(O)R • Allyl-X → Allyl-SR • Sulfide → Sulfoxide • O-C(O)R → O-H • O-H → O-SO2R • CarboxEster → CarboxAcid • 2,3-Sigmatropic Sulfoxide • Pummerer • Acetal(thio) → Aldehyde • Wittig-alkyl → Ene-cis • Allyl-X → Allyl-SR • Mechanism •
Reagents: BuLi(n) • Benzoyl chloride • Acetic anhydride, trifluoro • Acetate, sodium • Thiol, phenyl • Carbonate, potassium • Perbenzoic acid, 3-chloro • Carbonate, calcium • HgCl2 • Carbonate, potassium • Sulfonyl chloride, methane, NEt3 • Carbonate, potassium • Hydroxide, lithium •

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