Effect of PMDTA on Reaction with Ester

  

- The monomeric PMDTA complex of the enolate of dibenzyl ketone (p-F) is more reactive than THF-complexed dimer by factor of 9 in an Aldol reaction
- Here PMDTA suppresses the rate of addition to the ester -- dimer reaction more favorable? Lewis acidity of Li reduced?


Web page created by WINPLT