image

Total synthesis of Brevicomin, exo:
Reference: Matteson, D. S.; Sadhu, K. M. J. Am. Chem. Soc. 1983, 105, 2077. DOI
Keywords: Ketal -> Ketone • O-Bn -> O-H • Li-Dichloromethyl+Borane • Mg-Alkyl+Borane • Metalate rearrangement (B) • Metalate rearrangement (B) •
Reagents: LiCHCl2 • ZnCl2 • LiOCH2Ph • LiCHCl2 • ZnCl2 • H2O2, NaOH • H2, Pd • EtMgX •

Syntheses Home