| Reference: | Fujisawa, T.; Nagai, M.; Koike, Y.; Shimizu, M. J. Org. Chem. 1994, 59, 5865. DOI |
| Keywords: | N-Boc -> N-H • N-H -> N-C(O)NR2 • O-H -> O-SO2R • Li-Alkynyl+Aldehyde • Hydrogenation-Enesulfide • Felkin-Anh Chelation control • N-H -> N-Alkyl(2°) • Alkyne Hydrosulfidation • Sulfide-5 • |
| Reagents: | Alkynyl-ZnX • TsOH • Isocyanate • KH • HMPA (solvent) • TsOH • Hydroxide, cesium • H2, Pd • HBr • Microbial oxidation • |