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Total synthesis of Aspidospermine Model:
Reference: Magnus, P.; Cairns, P. M.; Kim, C. S. Tetrahedron Lett., 1985, 26, 1963. DOI
Keywords: Sulfide -> Sulfoxide • Retro-Diels-Alder, cyclopentadiene • Pummerer • CarboxAcid -> CarboxCl • Singlet oxygen+Furan • Diels-Alder, o-xylylene, intram • Lactam-6 • Decarboxylative elimination • Aldehyde -> Imine • CarboxAcid -> CarboxAmide • Wittig-methyl • Diels-Alder, EneLactone •
Reagents: Perbenzoic acid, 3-chloro • Acetic anhydride, trifluoro • Sieves • O2 (singlet) • Ph3P=CH2 • Oxalyl chloride •

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