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Total synthesis of Camptothecin:
Reference: Tang, C.; Rapoport, H. J. Am. Chem. Soc. 1972, 94, 8615
Keywords: Ketone -> Alkyl-OH • O-C(O)OR -> O-H • Alkyl-OH -> Ketone • Allylic oxidation -> Allyl-OH • Hoffmann elim -> Enoate • Allylic oxidation -> Allyl-OH • Claisen-Johnson • Friedlander • CarboxEster -> CarboxEster-α-OH •
Reagents: BH4-Na+ • Acetic anhydride • SeO2 • Acetic acid • Carbonate, potassium • Carbodiimide • SeO2 • H2SO4 • CuCl • DMF (solvent) • O2

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