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Total synthesis of Bakkenolide:
Reference: Evans, D. A.; Sims, C. L.; Andrews, G. C. J. Am. Chem. Soc. 1977, 99, 5453
Keywords: Alkene cleavage • CarboxEster(thio) -> CarboxEster(thio) • Enone enolate+Allyl-X • Aldol-K -> Enone • Hydrogenation-Enone • Li-Vinyl+Enone • Allyl-OH -> Allyl-Br • Allyl-X -> Allyl-SR • 2,3-Sigmatropic Anionic • Allylic oxidation -> Allyl-OH •
Reagents: KOtBu • Hydroxide, potassium • OsO4, NaIO4 • KOtBu • H2, Pd • Vinyl-Li • PBr3 • NaH • NaH • HgCl2 • SeO2

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