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Total synthesis of Atrylacton:
Reference: Minato, H.; Nagasaki, T Chem. Comm. 1965, 377. DOI
Keywords: Ketone -> Ketal • Nitrile -> Aldehyde • Cope elimination • Ketal -> Ketone • CarboxEster -> CarboxAcid • ConjAdd M-CN • Nitrile -> Amine • Reductive amination, B-H • Wolff-Kishner • Ketone -> CH2 • Amine -> AmineOxide • Furan synthesis • Ketone enolate+Bromoacetate •
Reagents: AlEt3 • HCN • Glycol • H2, Pd • Formaldehyde • BH4-Na+ • AlHiBu2 • Hydrazine • Perbenzoic acid, 3-chloro • Acetic acid • Bromoacetate • Carbonate, potassium • Acetic anhydride • AlEt2-CN •

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