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Total synthesis of Amphidinol 3 (Part 2):
Reference: Huckins, J. R.; Vicente, J. de; Rychnovsky, S. D. Org. Lett. 2007, 9, 4757. DOI
Keywords: O-SiMe2tBu -> O-H • Alkyl-OH -> Aldehyde • O-H -> O-C(O)R • O-H -> O-SiMe2tBu • CarboxAcid -> CarboxAmide(Weinreb) • Nozaki-Hiyama coupling • Cr-Vinyl+Aldehyde • Claisen-Ireland • Li/S -> Li-Alkyl • CarboxAmide(Weinreb)+Li-Alkyl •
Reagents: BuLi(n) • LiDBB • Fluoride, Bu4N+ • Dess-Martin • Propenyl-Br • CrCl2 • DMAP • SiMe2tBu-OTf • Acetic acid • NMe(OMe)-H • Carbodiimide •

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