Course Announcement

Chem 801: Kinetics and Catalysis with Organotransition Metal Complexes

Instructor Professor Clark Landis

Time 2:25-3:45 TR (additional workshop sessions to be scheduled)

Location B355 Chem

Credits 3

This inaugural offering will introduce three intertwined themes: fundamental reactions of organotransition metal complexes, condensed phase kinetic methods, and the kinetics of catalytic processes. In addition to lectures and readings, the course will make extensive use of Mathcad and Excel for the analysis and presentation of kinetics results. A weekly workshop will be used for software training and to work on exercises. Listed below are some of the topics to be introduced in this course.

I. Kinetics Measurements and Analyses

Rate Laws for Reversible and Irreversible Elementary Steps

Kinetic Measurements

Spectroscopic Methods

Rapid Mixing Approaches

Relaxation Methods (esp. Magnetization Transfer)

Isotope Exchange

Methods of Analysis

Instantaneous Rate Methods

Integrated Rate Laws

Numerical Integration (Runge-Kutta) Methods

Matrix Methods

Error Analysis

Rate Laws for Multi-step Reactions

Steady-State Approximation

Catalysis and the Turnover-Limiting Step

II. Organotransition Metal Reactions

Electron Counting and Structure

Substitution Reactions

Oxidative Addition/Reductive Elimination

Migratory Insertion Reactions

III. Case Studies in Catalysis

Hydrogenation/Dehydrogenation

Alcohol Carbonylation

Alkene Metathesis